In Singapore, doctor-prescribed weight loss injection pens have become an important option for individuals seeking medical support for weight management. These treatments include once-weekly and daily GLP-1 receptor agonist injections, which are internationally recognised and available under various brand names.
These prescription pens deliver medications such as semaglutide, tirzepatide, and liraglutide. By acting on appetite regulation and metabolic pathways, these treatments may support weight reduction in suitable patients under medical supervision.
Weekly injection pens containing semaglutide are available in both standard (0.25–1mg) and higher-dose (up to 2.4mg) versions. The dual agonist injection pen with tirzepatide is a more recent development, while the daily liraglutide injection pen is a well-established option for weight management.
This guide provides an overview of GLP-1 and dual agonist weight loss injection pens in Singapore, including their mechanisms of action, who may be eligible for treatment, and what to expect during the process.
GLP-1 and dual agonist weight loss injection pens are doctor-prescribed medications used in Singapore to assist with medical weight management in adults with overweight or obesity.
These injectable treatments are administered as either once-weekly or daily injections, depending on the medication, and act on hormonal pathways that regulate appetite, satiety, and metabolism.
Several active ingredients are used in these pens, including semaglutide, tirzepatide, and liraglutide. All require a medical consultation, prescription, and ongoing monitoring to ensure safety and suitability.
Prescription weight loss injection pens in Singapore are available as both weekly and daily options. The main types are:
Each option is chosen based on clinical assessment and individual needs. For dosing details and specific indications, see the section below.
These ingredients work by supporting appetite regulation, calorie reduction, and improved metabolic control.
Weight loss injection pens help reduce body weight by targeting hormones that influence hunger, fullness, and energy balance. These mechanisms make them effective as part of a comprehensive, medically supervised weight management plan.
GLP-1 receptor agonists such as semaglutide and liraglutide mimic the effects of the natural GLP-1 hormone, increasing satiety, reducing hunger, and slowing gastric emptying. This can result in decreased caloric intake and gradual, sustained weight loss.
Dual agonist injections with tirzepatide activate both GLP-1 and GIP pathways, providing an additional effect on appetite and glucose control, which may lead to greater weight reduction for some individuals.
The most appropriate dosing schedule is determined by a doctor during the initial assessment and follow-up consultations.
This section details each type of weight loss injection pen available in Singapore, including specific dosing, titration protocols, and unique considerations for each medication.
The once-weekly semaglutide pen is prescribed at standard doses ranging from 0.25mg to 1mg. It is indicated for both type 2 diabetes and weight management.
Treatment typically starts at the lowest dose, with gradual increases based on clinical response and tolerance. This pen offers a familiar and convenient weekly regimen for many patients.
A high-dose version of the once-weekly semaglutide pen is specifically indicated for weight management in adults with overweight or obesity.
Dosing begins at 0.25mg and is increased over several weeks up to a maximum of 2.4mg weekly, as guided by your doctor. This escalation protocol is designed to minimise side effects while achieving optimal results.
The tirzepatide injection pen is a next-generation, dual agonist therapy targeting both GLP-1 and GIP receptors for enhanced weight loss support.
It is available in multiple dosing strengths: 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg, and 15mg.
Treatment usually starts at the lowest available dose, with titration at regular intervals to achieve the desired therapeutic effect while monitoring for tolerability and efficacy.
The daily liraglutide injection pen is administered once daily and is suitable for adults requiring a more frequent dosing schedule.
Dosing is initiated at a lower strength and gradually increased based on patient response. This established GLP-1 agonist is chosen for patients who may not tolerate weekly injections or who respond best to a daily regimen.
Prescription weight loss injection pens—including those containing semaglutide, tirzepatide, or liraglutide—are not suitable for everyone. These treatments are intended for adults who meet specific clinical criteria and should only be started after a comprehensive medical assessment by a qualified doctor in Singapore.
Weight loss injection pens with semaglutide, tirzepatide, or liraglutide may be considered for adults who:
These criteria apply to all GLP-1 and dual agonist treatments, including once-weekly semaglutide or tirzepatide injections and daily liraglutide injections.
Before prescribing semaglutide, tirzepatide, or liraglutide injection pens, your doctor will conduct a detailed medical evaluation. This includes a review of your health history, current medications, and any relevant risk factors. These prescription treatments are generally not recommended for:
Your doctor will also consider any other health conditions that may affect the safety of using a GLP-1 or dual agonist medication.
Patients prescribed semaglutide, tirzepatide, or liraglutide for weight loss will require regular follow-up appointments. Your doctor will monitor your progress, review any potential side effects, and adjust your dosing as needed to ensure continued safety and effectiveness of the treatment.
Understanding the treatment process helps patients prepare for safe and effective weight loss using prescription injection pens, including those containing semaglutide, tirzepatide, or liraglutide.
Your weight management journey begins with a medical consultation at a licensed clinic in Singapore. During this appointment, your doctor will review your medical history, calculate your body mass index (BMI), and discuss your weight loss goals.
Suitability for a GLP-1 injection pen containing semaglutide or liraglutide, or a dual agonist injection pen containing tirzepatide, is determined based on clinical guidelines and your individual needs.
If eligible, your doctor will prescribe the most appropriate injection pen and provide clear instructions on self-administration. For semaglutide and tirzepatide, treatment usually starts at a lower dose with gradual titration over several weeks to reach the maintenance dose.
Liraglutide, as a daily GLP-1 injection, also follows a gradual dose escalation to enhance tolerability. You will receive training on injection technique, the recommended dosing schedule (weekly for semaglutide or tirzepatide, daily for liraglutide), and safe storage of your medication.
Regular follow-up appointments are required to monitor your weight loss progress, check for side effects, and make any necessary adjustments to your dosing. Your doctor will review your response to semaglutide, tirzepatide, or liraglutide, and assess changes in weight and metabolic health.
Ongoing support and medical supervision are key to maximising the benefits and safety of your treatment.
Combining GLP-1 or dual agonist injection therapy with a reduced-calorie diet, increased physical activity, and healthy lifestyle habits further supports long-term weight loss.
Your doctor may provide or recommend additional resources for nutrition and exercise counselling to help you achieve and sustain your goals.
Numerous clinical trials and real-world studies have demonstrated the effectiveness of GLP-1 receptor agonists and dual agonist injections, such as semaglutide, tirzepatide, and liraglutide, for medical weight management in adults with overweight or obesity.
While results can vary from person to person, many patients in Singapore have achieved significant, sustained weight loss with semaglutide, tirzepatide, or liraglutide injections as part of a comprehensive doctor-supervised programme.
Weight reduction is typically gradual, with the greatest changes seen in the first six to twelve months of treatment.
Ongoing follow-up with your doctor is essential to maximise benefits, monitor side effects, and support long-term success. Combining medication with dietary adjustments and increased physical activity is recommended for best outcomes.
Understanding the potential side effects and safety considerations of prescription weight loss injection pens—such as semaglutide, tirzepatide, and liraglutide—is essential for patients considering GLP-1 or dual agonist therapies in Singapore.
Careful medical supervision and regular follow-up help minimise risks and ensure the safe use of these medications.
Most patients experience mild to moderate side effects when starting GLP-1 or dual agonist weight loss injections. The most frequently reported include:
These side effects are usually temporary and tend to improve as the body adjusts to the medication. Starting at a lower dose and gradually increasing the dosage can help minimise these symptoms.
Although uncommon, some patients may experience more serious side effects, including:
GLP-1 and dual agonist weight loss injections are generally not recommended for individuals with a personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, or a history of severe gastrointestinal disease.
It is important to inform your doctor about all your medical conditions before starting treatment.
Patients prescribed semaglutide, tirzepatide, or liraglutide injection pens will have regular follow-up appointments to monitor for side effects, review lab results, and assess overall response to treatment.
Always contact your doctor immediately if you experience severe abdominal pain, symptoms of an allergic reaction, or any new or concerning side effects during treatment.
Prompt reporting and medical evaluation help ensure that potential complications are identified early and managed appropriately.
Starting prescription weight loss injection therapy, such as GLP-1 or dual agonist injections (semaglutide, tirzepatide, or liraglutide), requires careful medical supervision to ensure safety and optimal results. Here’s what to expect when beginning your treatment journey in Singapore:
Your first step is to schedule an appointment with a doctor experienced in weight management. During the consultation, your medical history, body mass index (BMI), and previous weight loss attempts will be reviewed to determine eligibility for a prescription weight loss injection pen.
If you meet clinical criteria, your doctor will conduct a thorough evaluation to select the most appropriate medication—such as a once-weekly semaglutide or tirzepatide injection, or a daily liraglutide injection. The prescription will include a starting dose and a titration plan based on your individual needs and safety profile.
You will receive detailed instructions on how to use your injection pen, including safe injection techniques, storage requirements, and a dosing schedule. The clinic team will demonstrate the process and answer any questions to ensure you are comfortable and confident in self-administration.
After starting treatment, you will have regular follow-up visits to monitor progress, adjust dosing if needed, and address any side effects or concerns. Ongoing medical supervision helps maximise weight loss results while maintaining safety.
To begin your weight loss journey with a prescription injection pen, book a consultation with our clinic today. Our doctor will provide a personalised assessment and guide you through every step of the process.
Understanding the differences between available GLP-1 and dual agonist weight loss injection pens helps patients and clinicians select the most suitable treatment.
The main injectable medications prescribed in Singapore for medical weight management are semaglutide, tirzepatide, and liraglutide.
Individual results vary, and maximum benefit is usually achieved with ongoing medical supervision and healthy lifestyle changes.
Feature | Semaglutide | Tirzepatide | Liraglutide |
Class | GLP-1 receptor agonist | Dual GLP-1/GIP agonist | GLP-1 receptor agonist |
Dosing Frequency | Once weekly | Once weekly | Once daily |
Available Dose Range | 0.25mg to 2.4mg/week | 2.5mg to 15mg/week | 0.6mg to 3mg/day |
Average Weight Loss* | 10–15% (STEP trials) | Up to 20% (SURMOUNT trials) | 5–8% (SCALE trials) |
Most Common Side Effects | Nausea, GI upset | Nausea, GI upset | Nausea, GI upset |
Indication | Obesity, diabetes | Obesity | Obesity, diabetes |
* Average weight loss reflects clinical trial results with lifestyle intervention. Individual results may vary.
The choice between semaglutide, tirzepatide, and liraglutide depends on individual medical history, body mass index (BMI), treatment goals, preferences, and potential for side effects.
A comprehensive assessment by your doctor is essential to determine the most appropriate option for safe and effective weight management.
Selecting a reputable and experienced clinic is essential when starting prescription weight loss injection therapy with GLP-1 or dual agonist medications such as semaglutide, tirzepatide, or liraglutide.
Proper medical supervision helps ensure your safety, treatment effectiveness, and ongoing support throughout your weight loss journey.
To begin treatment with prescription weight loss injection pens in Singapore, schedule a consultation with a licensed medical aesthetic clinic.
During your visit, the doctor will perform a medical evaluation, discuss your goals, and recommend the most suitable option—such as semaglutide, tirzepatide, or liraglutide injections.
For more information or to book an appointment, please contact our clinic.
What Is the Difference Between the Weekly Semaglutide Injection Pen and the Daily GLP-1 Injection Pen?
The weekly semaglutide injection pen—known internationally under names such as Ozempic and Wegovy—requires a single injection each week, while the daily GLP-1 injection pen (commonly recognised as Saxenda) is administered once per day. Your doctor will recommend the most suitable option based on your medical profile and lifestyle needs.
How Much Weight Can I Expect to Lose With High-Dose Weekly Weight Loss Injection Pens or Dual Agonist Injections?
High-dose weekly injection pens containing semaglutide (such as Wegovy) have demonstrated average weight loss of 10–15% of initial body weight in clinical trials. Dual agonist injection pens containing tirzepatide (like Mounjaro) have shown even greater results, with some patients achieving up to 20% weight loss in studies. Individual results depend on various factors, including adherence and lifestyle changes.
Is the Dual Agonist Weekly Injection Pen Available in Singapore?
The dual agonist weekly injection pen—containing tirzepatide and recognised overseas as Mounjaro—is becoming more accessible in Singapore through licensed medical clinics. Please contact our clinic for the latest updates on availability and prescription requirements.
What Is the Difference Between the Standard Weekly Semaglutide Injection and the High-Dose Version?
Both the standard and high-dose weekly semaglutide injection pens contain the same active ingredient but differ in maximum dose. The standard pen (often called Ozempic) is primarily for diabetes management and can support weight loss, while the high-dose version (Wegovy) is specifically indicated for obesity and supports doses up to 2.4mg weekly.
Who Is Eligible for Weekly Semaglutide, Dual Agonist, or Daily GLP-1 Injection Pens?
Eligibility is typically based on your BMI, presence of weight-related medical conditions, and previous response to lifestyle modifications. Weekly semaglutide (Ozempic, Wegovy), dual agonist (Mounjaro), and daily GLP-1 (Saxenda) injection pens are usually prescribed for adults with a BMI of 27 kg/m² and above, or 30 kg/m² and above without comorbidities.
What Are the Common Side Effects of Weekly or Daily GLP-1 and Dual Agonist Injections?
All GLP-1 and dual agonist injections, including those sold as Ozempic, Wegovy, Mounjaro, and Saxenda, may cause gastrointestinal side effects such as nausea, vomiting, diarrhoea, and reduced appetite. Most symptoms are mild and improve over time, especially with gradual dose escalation under medical supervision.
How Are Weekly and Daily Injection Pens Administered?
Weekly injection pens (Ozempic, Wegovy and Mounjaro) are administered once a week via subcutaneous injection, while daily pens (Saxenda) are used every day. Your doctor will provide full training on injection technique and safe medication handling.
Can I Switch From a Daily to a Weekly Injection Pen, or Between Different Weekly Injections?
Switching between GLP-1 and dual agonist injection pens may be recommended if you do not achieve satisfactory results or experience side effects. Transitioning between options such as Saxenda, Ozempic, Wegovy, or Mounjaro should always be managed by your doctor, who will develop a personalised protocol for safe switching.
What Is the Price Range for Weekly and Daily Weight Loss Injection Pens in Singapore?
The cost of weekly and daily prescription weight loss injection pens varies by medication, dose, and clinic. Generally, newer options such as Wegovy and Mounjaro are priced higher than standard semaglutide (Ozempic) or daily liraglutide (Saxenda). Contact our clinic for current pricing and available packages.
How Do I Start Treatment With a Weekly Semaglutide, Dual Agonist, or Daily GLP-1 Injection Pen in Singapore?
To begin treatment with any of these prescription injection pens, book a consultation with a qualified doctor in Singapore. After a detailed assessment, your doctor will determine whether you are suitable for options such as Ozempic, Wegovy, Mounjaro, or Saxenda, and provide you with full guidance and ongoing support.
Can Weekly or Daily Weight Loss Injection Pens Be Combined With Other Weight Management Treatments?
Prescription weight loss injection pens such as Ozempic, Wegovy, Mounjaro, or Saxenda are typically used as stand-alone medical therapies. Combining these with other prescription weight loss medications is not recommended unless advised by your doctor. They may, however, be used alongside lifestyle interventions, such as a reduced-calorie diet, regular exercise, and behavioural support.
How Long Does It Take to See Results From Weekly or Daily GLP-1 or Dual Agonist Injections?
Patients using medications like Ozempic, Wegovy, Mounjaro, or Saxenda may begin to notice weight loss within the first few weeks of treatment. Most significant results are observed over three to six months, with ongoing improvement for as long as treatment continues and lifestyle changes are maintained.
Are Prescription Weight Loss Injection Pens Safe for Long-Term Use?
GLP-1 and dual agonist injection pens (such as Ozempic, Wegovy, Mounjaro, and Saxenda) have been studied for safety in long-term clinical trials. While they are considered safe for ongoing use under medical supervision, your doctor will regularly monitor your progress and adjust treatment as needed to minimise risks and manage any side effects.
What Should I Do If I Miss a Dose of My Weekly or Daily Injection Pen?
If you miss a dose of your weekly injection pen (such as Ozempic, Wegovy, or Mounjaro), take the missed dose as soon as you remember if it is within a few days, then resume your regular schedule. For daily pens (like Saxenda), take the missed dose as soon as possible but skip it if it’s almost time for your next scheduled dose. Always follow your doctor’s instructions for missed doses.
Can These Weight Loss Injection Pens Be Used for Diabetes and Weight Management?
Certain injection pens, such as Ozempic and Saxenda (both containing semaglutide and liraglutide, respectively), were initially developed for type 2 diabetes management and are now also approved for weight loss. Wegovy and Mounjaro are specifically indicated for weight management but may also have benefits for blood sugar control in some patients. Your doctor will prescribe the most appropriate option based on your health profile.
Are There Any Dietary Restrictions While Using Weekly or Daily Weight Loss Injection Pens?
There are no strict dietary restrictions while using GLP-1 or dual agonist injection pens such as Ozempic, Wegovy, Mounjaro, or Saxenda. However, for optimal results, a reduced-calorie, balanced diet and regular physical activity are strongly recommended. Your doctor or clinic may provide additional dietary guidance to maximise treatment effectiveness.
Is Prior Authorisation or Special Approval Needed to Start Weekly or Daily Injection Pen Therapy in Singapore?
All prescription weight loss injection pens, including options like Ozempic, Wegovy, Mounjaro, and Saxenda, require a valid doctor’s prescription in Singapore. No special authorisation is needed beyond your doctor’s assessment, but not all clinics may offer every option. Booking a medical consultation is the first step.
What Should I Do If I Experience Side Effects From My Weekly or Daily Injection Pen?
If you experience mild side effects (such as nausea or mild stomach upset) from your weight loss injection pen (Ozempic, Wegovy, Mounjaro, or Saxenda), notify your doctor at your next follow-up. For severe symptoms such as persistent vomiting, dehydration, or severe abdominal pain, seek medical attention promptly. Dose adjustments or alternative medications may be recommended.
Can I Use a Weekly or Daily Weight Loss Injection Pen if I Am Planning Pregnancy?
Prescription weight loss injection pens (including Ozempic, Wegovy, Mounjaro, and Saxenda) are not recommended during pregnancy or if you are planning to conceive. Inform your doctor if you are pregnant, breastfeeding, or planning pregnancy so that appropriate alternatives can be discussed.
Are Weight Loss Injection Pens Suitable for Younger Adults or Teenagers?
Most weekly and daily weight loss injection pens, such as Ozempic, Wegovy, Mounjaro, and Saxenda, are approved for adults aged 18 and above. Use in adolescents or children is not routinely recommended unless specifically approved and supervised by a specialist.
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