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Structura Injectable Moisturiser Singapore – Italian 90mg HA Lipolifting & Volume Restoration Skinbooster

Structura Injectable Moisturiser is an Italian-formulated 90mg hyaluronic acid (HA) skinbooster available in Singapore. Created by the team behind the first injectable moisturiser concept, Structura is engineered for subcutaneous injection to address age-related facial volume loss through lipolifting and tissue support.

This injectable utilises a dual molecular weight HA hybrid complex, made possible by patented NAHYCO® technology. By targeting deep fat compartments, Structura helps to restore facial fullness and improve the appearance of mid-face hollowing, sagging, and changes in skin quality.

Structura Injectable Moisturiser is suitable for individuals seeking a non-surgical method to manage volume loss and achieve gradual, natural-looking facial enhancement.

Overview of Structura Injectable Moisturiser in Singapore

Learn how Structura Injectable Moisturiser, an Italian-formulated 90mg HA injectable, is used in Singapore to address facial volume loss and support subcutaneous lipolifting. This structural skinbooster was developed by the same team that introduced the original injectable moisturiser concept, using patented hybrid technology to deliver sustained tissue support and hydration.

Development and Technology of Structura Injectable

Structura was developed by a group of Italian researchers who first pioneered the use of injectable moisturisers for skin quality improvement. The goal with Structura was to design an injectable that targets not just hydration but also deep structural support through subcutaneous fat compartment restoration. This new approach builds on years of clinical experience with earlier skinboosters.

Dual Molecular Weight HA and NAHYCO® Hybrid Complex

Each syringe of Structura contains 90mg of hyaluronic acid in both high and low molecular weights, produced with NAHYCO® hybrid technology. This process thermally combines HA molecules without chemical cross-linking, resulting in a hybrid complex that remains stable within the deeper layers of facial tissue and gradually integrates for longer-lasting support.

How Structura Differs from Other Injectable Moisturisers

Structura is distinct from earlier Italian injectable moisturisers, which contain 64mg of hyaluronic acid per syringe and are primarily intended for superficial hydration and improvement in skin texture.
In comparison, Structura features a higher concentration of 90mg HA per syringe, together with NAHYCO® hybrid technology and a subcutaneous injection technique. This allows Structura to target deeper facial tissue, supporting volume restoration and lipolifting—addressing age-related hollowing and soft tissue changes more effectively than previous formulations.

Mechanism of Lipolifting and Volume Restoration with Structura

Understanding the mechanism behind Structura Injectable Moisturiser helps patients in Singapore make informed choices for managing facial volume loss and age-related changes. 

This Italian-formulated skinbooster is engineered for subcutaneous injection, directly targeting deep fat compartments to restore facial fullness and provide gradual tissue enhancement.

Targeting Subcutaneous Fat Compartments

Structura Injectable Moisturiser is designed for administration with a blunt-tip cannula, which allows for safe and precise placement of hyaluronic acid within the subcutaneous fat layers of the face.

These compartments, including the malar and submalar fat pads, are critical for maintaining youthful mid-face volume and support. Age-related volume loss in these regions often results in flattening of the cheeks, development of nasolabial folds, and a sunken appearance.

By delivering 90mg of dual molecular weight hyaluronic acid directly to these compartments, Structura aims to replenish lost volume, support soft tissue architecture, and restore more youthful facial contours.
The injection technique helps avoid important blood vessels and minimises the risk of bruising or vascular complications.

Tissue Integration and Gradual Volume Enhancement

The hybrid NAHYCO® complex in Structura allows the product to integrate gradually with surrounding tissue, providing both immediate and long-term effects. The hydrophilic nature of hyaluronic acid attracts and binds large amounts of water, leading to increased hydration and expansion of local tissues.

Clinical studies using ultrasound imaging have demonstrated a measurable increase in tissue thickness and mid-face fullness following Structura treatment, with improvements often seen after two sessions spaced 4 to 6 weeks apart.

The gradual tissue integration of Structura supports a natural lifting effect—often referred to as “lipolifting”—that restores volume without abrupt changes or the firm, rigid feel sometimes associated with traditional cross-linked fillers.

Patients typically observe subtle improvements over several months, as the hybrid HA complex continues to support the extracellular matrix and maintain soft tissue volume.

Role of Dual Molecular Weight HA in Structural Support

Structura Injectable Moisturiser uses a combination of high and low molecular weight hyaluronic acid (HA), with 45mg of each per syringe.

This formula is created with patented NAHYCO® hybrid technology, which thermally combines the HA molecules instead of using chemical cross-linking. The result is a stable hybrid complex that stays active longer in the subcutaneous fat compartments beneath the skin, supporting both hydration and volume restoration.

Because Structura’s dual molecular weight HA resists rapid breakdown, it continues to provide a volumising and lipolifting effect over several months.
Preclinical research suggests that this hybrid HA matrix may help stimulate the body’s own fat cell activity (adipocyte progenitor cells) and strengthen the tissue’s support structure (extracellular matrix), leading to gradual, long-term improvement in facial fullness.

Unlike classic injectable moisturisers, which usually contain 64mg of HA and are meant for superficial skin hydration, Structura has a higher HA content (90mg per syringe) and is injected deeper.

This provides immediate hydration to deeper tissues as well as sustained mechanical lift and support to the face. Structura is especially suitable for patients looking to address mid-face hollowing, age-related sagging, and gradual facial volume loss in a natural, progressive manner.

Clinical Applications and Treatment Areas for Structura Injectable Moisturiser

Structura Injectable Moisturiser is used in Singapore to address the specific areas of the face most affected by age-related volume loss. By targeting these regions, this Italian 90mg HA skinbooster offers patients a non-surgical option to restore natural facial fullness and soft tissue support.

Commonly Treated Facial Regions

Structura is most often used to restore volume in the mid-face, including the malar (cheekbone) and submalar (under-cheek) fat pads, which are commonly affected by ageing.

Other popular treatment areas include the jawline, chin, temples, and preauricular region (area in front of the ears). Treatment is individualised based on each patient’s anatomy and facial rejuvenation goals.

Patient Suitability and Assessment

Suitable candidates for Structura Injectable Moisturiser are adults experiencing facial hollowing, sagging, or loss of fullness, particularly in the mid-face and lower face.

The treatment is appropriate for those seeking gradual, natural-looking enhancement without the rigidity of traditional fillers. A thorough consultation in Singapore is necessary to assess facial structure, volume loss, skin condition, and medical suitability before proceeding.

Combining Structura with Other Injectable Treatments

Structura Injectable Moisturiser can be safely combined with other injectable treatments for a comprehensive, personalised facial rejuvenation strategy.

Many patients in Singapore choose to pair Structura with botulinum toxin injections to soften dynamic wrinkles and lines, and with hyaluronic acid dermal fillers to address specific areas of volume loss that require more targeted augmentation.

In addition, Structura can be integrated into a regimen that includes polynucleotide skinboosters (often known as “salmon DNA injectables”) to improve skin texture and hydration, as well as hybrid collagen-stimulating injectables such as PDLLA-HA treatments for enhanced collagen production.

Biostimulating fillers—containing active ingredients that gradually stimulate the body’s own collagen, such as polycaprolactone (PCL) or poly-L-lactic acid (PLLA) injectables—may also be used alongside Structura to further improve skin firmness and support.

The choice of combination treatments depends on each patient’s unique aesthetic needs, facial anatomy, and treatment goals. A customised plan is developed in consultation with a qualified doctor to ensure safe and natural-looking results.

Treatment Process and What Patients Can Expect with Structura Injectable Moisturiser 

Understanding each step of the Structura Injectable Moisturiser treatment process in Singapore helps patients know what to anticipate before, during, and after their procedure. This ensures realistic expectations and a smooth treatment experience.

Pre-Treatment Consultation and Planning

The process begins with a detailed consultation, where the doctor will assess facial structure, degree of volume loss, and overall skin health.

Medical history and treatment goals are discussed to determine suitability for Structura Injectable Moisturiser and to create a personalised plan. Photographs may be taken for baseline comparison.

Injection Technique and Safety Considerations

On treatment day, the face is cleansed and marked to guide injection placement. Structura is administered using a blunt-tip cannula to carefully deliver the product into the subcutaneous fat compartments.

This technique allows for even product distribution and helps minimise the risk of bruising, swelling, or vascular injury. The procedure typically takes about 15–30 minutes, depending on the areas treated.

Downtime, Recovery, and Aftercare

Most patients experience only mild swelling, tenderness, or occasional bruising at the injection sites. These effects usually resolve within a few days.

Patients are advised to avoid strenuous exercise, heat exposure, alcohol, and vigorous facial massage for at least 24–48 hours after treatment. Your doctor will provide individualised aftercare instructions to support optimal results and recovery.

Maintenance and Long-Term Care

Structura Injectable Moisturiser is generally performed as a series of two sessions, spaced four to six weeks apart.

Maintenance treatments every 6 to 12 months may be recommended to preserve facial volume and the benefits of lipolifting. Regular reviews allow the treatment plan to be adjusted as your needs evolve over time.

Scientific Studies and Clinical Results for Structura Injectable Moisturiser

Several published clinical studies support the use of Structura Injectable Moisturiser (Italian 90mg HA skinbooster) for restoring facial volume and improving age-related tissue changes in Singapore. These studies provide strong evidence for its effectiveness, safety, and patient satisfaction in both clinical and real-world settings.

Clinical Evidence for Volume Restoration and Tissue Improvement

A key pilot study involving 50 healthy patients investigated the results of two Structura Injectable Moisturiser sessions (each 2 ml, spaced one month apart) targeted at the lateral cheek fat compartment.

After three and four months, both the Facial Volume Loss Scale (FVLS) and Wrinkle Severity Rating Scale (WSRS) showed statistically significant improvements. Patients experienced increased fullness in the cheeks, reduction in visible wrinkles, and enhanced overall facial appearance.

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Ultrasound and 3D Imaging Data

Ultrasound scans and 3D photographic analysis performed in clinical trials confirmed a measurable increase in subcutaneous tissue thickness at 3 and 6 months following Structura treatment.

These objective imaging results support the product’s gradual integration, tissue support, and volumising effect.

Study summary

Patient Satisfaction and Safety

Patient-reported outcomes in the studies demonstrated high satisfaction, with more than 77% of patients noting visible improvements in firmness, contour, and skin quality.

The safety profile was favourable, with only minor and transient side effects such as swelling or bruising at the injection sites. No serious adverse events were observed in the published studies.

Related reference

What Results and Safety Can Patients Expect from Structura Injectable Moisturiser?

Understanding the expected results and safety profile of Structura Injectable Moisturiser helps patients make informed decisions about this Italian 90mg HA skinbooster. Below is a summary of the real-world outcomes reported in both clinical studies and daily practice.

Improvements in Facial Volume and Skin Quality

Structura Injectable Moisturiser has been shown to restore lost volume in important facial areas such as the mid-face, cheeks, and jawline. Patients often notice a gradual return of facial fullness, softer contours, and improved facial harmony. 

In addition to volume restoration, many patients also experience smoother skin texture and better overall hydration, with these changes typically becoming noticeable within several weeks after treatment. 

As the product integrates into the tissues, the improvements continue to develop, resulting in a refreshed and more youthful appearance.

Duration of Results and Longevity

The effects of Structura Injectable Moisturiser are generally long-lasting. Most patients experience benefits for six to twelve months following a standard treatment protocol, which usually involves two sessions spaced about a month apart.

The unique dual molecular weight hyaluronic acid (HA) formulation and patented NAHYCO® hybrid technology help keep the product stable and effective within the facial fat compartments.

Maintenance treatments every 6 to 12 months can further extend and optimise these results, allowing patients to sustain facial volume and hydration over time.

Safety Profile and Adverse Events

Structura Injectable Moisturiser has a well-documented safety profile, supported by published clinical studies and daily use in medical aesthetic clinics across Singapore and internationally.

Most side effects are mild, temporary, and expected with injectable treatments. The most common reactions include swelling, redness, tenderness, or minor bruising at the injection sites. These effects typically resolve within a few days and do not interfere with work or daily routines.

For most patients, any discomfort is mild and can be easily managed with simple aftercare measures, such as applying a cold compress to the treated area and avoiding vigorous exercise, alcohol, or excessive heat for 24 to 48 hours post-procedure.

More serious complications, such as infection, nodules, or vascular events, are extremely rare when Structura is administered by a trained and experienced doctor using proper cannula technique and adhering to strict aseptic protocols.

Prior to treatment, a thorough consultation and medical assessment are carried out to minimise risks and ensure patient suitability.

Structura’s unique NAHYCO® hybrid technology formulation, with no chemical cross-linking, is designed to reduce the likelihood of allergic reactions or prolonged swelling. Compared to some traditional cross-linked fillers, the incidence of delayed lumps or persistent firmness is considered low.

If any unexpected side effects do occur, most are minor and reversible with conservative medical management. Patients are advised to contact their clinic if they experience symptoms such as persistent pain, spreading redness, or unusual swelling, so that timely support can be provided.

Overall, Structura Injectable Moisturiser is regarded as a safe, well-tolerated option for individuals seeking non-surgical facial volume restoration in Singapore, especially when performed by an experienced aesthetic doctor.

Choosing the Best Clinic for Structura Injectable Moisturiser in Singapore

Selecting a qualified clinic is crucial for safe and effective Structura Injectable Moisturiser treatment in Singapore. With the Italian 90mg HA skinbooster, optimal results depend on expert technique, a customised approach, and comprehensive patient care.

Experience with Italian 90mg HA Skinboosters

Look for a clinic that has specific experience with Italian 90mg HA injectable moisturisers and structural skinboosters. Understanding the unique mechanism and appropriate injection technique is essential to achieve gradual, natural-looking volume restoration and lipolifting without complications.

Personalised Assessment and Customised Treatment Plans

The best clinics provide thorough consultations and individualised treatment planning. A skilled doctor will assess your facial anatomy, degree of volume loss, and personal aesthetic goals before recommending Structura Injectable Moisturiser or any combination approach. This personalised strategy ensures safe, harmonious, and long-lasting results.

Safety, Comfort, and Post-Treatment Support

Safety should always be the top priority. Choose a clinic that uses proper injection techniques—such as blunt-tip cannulas—to reduce the risk of bruising or vascular events. Comprehensive aftercare support, clear post-treatment instructions, and follow-up reviews are also important for patient comfort and optimal results.

How to Book a Consultation for Structura Injectable Moisturiser

If you are considering non-surgical facial volume restoration in Singapore, schedule a consultation with our clinic to find out if Structura Injectable Moisturiser is right for you. Our doctors are experienced in structural skinboosters and will develop a tailored plan based on your needs and goals.

Comparing Structura Injectable Moisturiser to Other Injectable Treatments in Singapore

Patients considering non-surgical facial rejuvenation in Singapore often want to know how Structura Injectable Moisturiser—the Italian 90mg HA skinbooster—compares to other popular injectable options. 

Understanding the differences in formulation, mechanism, and clinical effect helps patients make informed choices for their unique needs.

Differences from Polynucleotide (“Salmon DNA”) Skinboosters

Polynucleotide (PN) skinboosters, commonly referred to as “salmon DNA injectables,” are designed to improve skin quality, texture, and hydration by stimulating cellular repair and regeneration in the superficial dermis. 

Unlike these treatments, Structura Injectable Moisturiser is engineered for deeper, subcutaneous injection to restore facial volume and provide a lipolifting effect. 

While PN skinboosters excel in treating fine lines, dullness, and mild scarring, Structura is more suitable for patients seeking to address mid-face hollowing, sagging, and age-related fat loss.

How Structura Compares to Hybrid Collagen-Stimulating Injectables

Hybrid collagen-stimulating injectables, such as PDLLA-HA treatments (often called “Korean collagen boosters”), combine hyaluronic acid with biostimulatory materials to promote new collagen formation and skin hydration.

These injectables are generally used for improving skin texture, firmness, and skin quality, particularly in younger patients or those with early signs of ageing.

Structura Injectable Moisturiser stands out due to its high concentration of dual molecular weight HA (90mg per syringe) and patented NAHYCO® hybrid technology, which are specifically intended for deep tissue support, volume restoration, and gradual, natural-looking lift.

Structura vs Traditional Dermal Fillers and Biostimulating Fillers

Traditional dermal fillers—made from cross-linked hyaluronic acid or biostimulating substances like polycaprolactone or poly-L-lactic acid—are commonly used to provide targeted volume enhancement, contouring, or structural augmentation of the face. While effective, these fillers can sometimes create a firmer or more rigid result, especially when used for deep tissue support. 

Structura Injectable Moisturiser, with its softer hybrid HA matrix and subcutaneous application, integrates more smoothly with natural tissues and offers a diffuse, subtle volume increase without excessive firmness. This makes it suitable for patients desiring more subtle results and a more natural feel.

When to Choose Structura Over Other Treatments

Structura Injectable Moisturiser may be the preferred option for adults experiencing mid-face or cheek hollowing, age-related sagging, or gradual loss of facial volume who wish to avoid the dense or sculpted effect of traditional fillers.

It is also suitable for patients who want a gradual, non-surgical lift with minimal downtime and a high safety profile. In some cases, a combination approach using Structura alongside PN skinboosters, hybrid collagen stimulators, or targeted dermal fillers can provide comprehensive facial rejuvenation tailored to each patient’s unique anatomy and goals.

Frequently Asked Questions About Structura Injectable Lipolifting Skinbooster

How Long Do Results from Structura Injectable Lipolifting Skinbooster Last?

Profhilo Structura typically delivers noticeable and lasting improvements in facial volume and skin quality. Most patients see results that last six to twelve months after completing the recommended two-session protocol, though duration may vary with individual lifestyle and metabolism.

Is Structura Injectable Lipolifting Skinbooster Safe for Facial Volume Restoration?

Profhilo Structura has demonstrated a strong safety profile in clinical studies and daily practice. Most side effects, such as mild swelling, redness, or bruising, are temporary and resolve within a few days. More serious complications are rare when treatment is performed by an experienced doctor using proper technique.

What Is the Treatment Process for Structura Injectable Lipolifting Skinbooster?

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Treatment involves an initial consultation, followed by injection with a blunt-tip cannula into the subcutaneous fat compartments of the face. The procedure is designed to be comfortable and efficient, typically requiring two sessions spaced 4 to 6 weeks apart for best results.

How Much Does Structura Injectable Lipolifting Skinbooster Cost in Singapore?

The cost of Profhilo Structura typically ranges from $1,200 to $1,800 per session in Singapore, depending on the amount of product required and individual facial anatomy. A consultation is necessary for a personalised quote.

Can Structura Injectable Lipolifting Skinbooster Be Combined with Other Treatments?

Yes, Profhilo Structura can be safely combined with other injectables, including polynucleotide skinboosters such as Rejuran (“salmon DNA injectables”), hybrid collagen-stimulating treatments like Juvelook, and biostimulating fillers based on PLLA or PCL technology (e.g., those similar to Ellanse or Sculptra). Combination approaches are customised according to your specific goals and facial anatomy.

Who Is a Suitable Candidate for Structura Injectable Lipolifting Skinbooster?

Profhilo Structura is ideal for adults with mid-face hollowing, sagging, or facial volume loss who desire a natural, non-surgical rejuvenation. It is especially suitable for those seeking subtle, progressive improvements without the density or firmness associated with traditional fillers.

What Are the Side Effects or Risks Associated with Structura Injectable Lipolifting Skinbooster?

Most side effects are mild and short-lived, such as swelling, redness, or bruising at the injection sites. These typically resolve quickly. Serious risks, including infection or vascular complications, are extremely rare when treatment is performed by a qualified doctor.

How Is Structura Injectable Lipolifting Skinbooster Different from Classic Injectable Skinboosters?

Profhilo Structura stands out from classic skinboosters, which usually contain 64mg of HA and focus on surface hydration. Structura offers a higher HA concentration (90mg) and is designed for deeper subcutaneous injection, providing volume restoration and lipolifting. It is particularly effective for addressing age-related fat loss and structural changes in the face.

How Many Sessions of Structura Injectable Lipolifting Skinbooster Are Needed?

Most patients require two sessions, spaced four to six weeks apart, for optimal results. Maintenance treatments every 6 to 12 months are often recommended to sustain the benefits.

What Is the Downtime After Structura Injectable Lipolifting Skinbooster Treatment?

Downtime is minimal. Patients may return to daily activities shortly after the procedure. Mild swelling or bruising may occur but typically resolves within a few days.

Which Facial Areas Can Be Treated with Structura Injectable Lipolifting Skinbooster?

Structura Injectable Lipolifting Skinbooster is most commonly used for the mid-face, cheeks, and jawline. It can also be adapted for other areas affected by age-related volume loss, such as the temples and chin.

Can Structura Injectable Lipolifting Skinbooster Be Repeated?

Yes, Structura Injectable Lipolifting Skinbooster can be safely repeated as part of a long-term rejuvenation plan. Your doctor will recommend an appropriate maintenance schedule based on your needs and goals.

Who Should Avoid Structura Injectable Lipolifting Skinbooster?

Profhilo Structura may not be suitable for individuals with known allergies to hyaluronic acid, active skin infections, or certain underlying medical conditions. It is generally not advised for pregnant or breastfeeding women.

How Does Structura Injectable Lipolifting Skinbooster Compare to Fillers and Other Skinboosters?

Structura Injectable Lipolifting Skinbooster differs from traditional dermal fillers by providing a softer, more diffuse volume restoration and natural lift, rather than rigid or sculpted augmentation. Compared to classic skinboosters and polynucleotide injectables like Rejuran or hybrid collagen stimulators like Juvelook, Structura delivers a higher concentration of hyaluronic acid (90mg) and is injected deeper, specifically targeting age-related fat loss and tissue support.

What Is the Difference Between Structura Injectable Lipolifting Skinbooster and Standard 64mg HA Skinboosters?

Structura Injectable Lipolifting Skinbooster contains 90mg of hyaluronic acid per syringe, compared to 64mg in standard injectable moisturisers. This higher HA content, combined with NAHYCO® hybrid technology, allows Structura to be injected into subcutaneous fat compartments for volume restoration and lipolifting, while most standard HA skinboosters are designed for superficial hydration.

Is Structura Injectable Lipolifting Skinbooster Suitable for Men?

Yes, Profhilo Structura is suitable for both men and women experiencing facial volume loss, sagging, or mid-face hollowing. The treatment protocol and injection technique can be tailored to achieve masculine or feminine facial proportions according to each patient’s aesthetic goals.

What Should I Avoid After Structura Injectable Lipolifting Skinbooster Treatment?

After treatment, it is recommended to avoid vigorous exercise, excessive heat (such as saunas), alcohol, and strong facial massage for 24 to 48 hours. These precautions help minimise swelling, bruising, and ensure optimal integration of the product.

When Will I See Results from Structura Injectable Lipolifting Skinbooster?

Most patients start to notice improvement in facial volume and skin quality within a few weeks after the first session. Full results typically develop after the second session, as the hyaluronic acid integrates into the tissues and stimulates natural soft tissue support.

Can Structura Injectable Lipolifting Skinbooster Be Used with Botulinum Toxin or Other Procedures?

Yes, Structura Injectable Lipolifting Skinbooster can be safely combined with botulinum toxin injections for wrinkle reduction or with other non-surgical procedures. Combination approaches are common in Singapore for achieving comprehensive facial rejuvenation.

Is There Any Preparation Required Before Structura Injectable Lipolifting Skinbooster?

Before your Structura treatment, your doctor may advise you to avoid blood-thinning medications or supplements (such as aspirin, fish oil, or vitamin E) to reduce the risk of bruising. Arriving with a clean, makeup-free face is also recommended.

How Do I Choose the Best Clinic for Structura Injectable Lipolifting Skinbooster in Singapore?

Look for a clinic with experience in structural skinboosters and a strong safety record. Choose a doctor who offers a thorough consultation, uses blunt-tip cannula technique, and provides ongoing aftercare. Booking a consultation allows for a personalised assessment and treatment plan.

What Is the Science Behind Structura Injectable Lipolifting Skinbooster?

Structura Injectable Lipolifting Skinbooster uses dual molecular weight hyaluronic acid and NAHYCO® hybrid technology to deliver a stable HA matrix into the subcutaneous fat compartments. This innovative approach supports natural volume restoration, gradual tissue integration, and a sustained lipolifting effect over time.

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