Wegovy is a once-weekly injectable medication that contains a higher dose of semaglutide, a compound that mimics the GLP-1 (glucagon-like peptide-1) hormone naturally produced by the body. Unlike other semaglutide medications such as Ozempic, which were originally developed for diabetes management, Wegovy is specifically formulated and approved for long-term weight loss.
By activating GLP-1 receptors in the brain and digestive system, Wegovy helps regulate appetite, reduce food cravings, and slow gastric emptying. These effects make it easier to eat less, feel full sooner, and maintain consistent dietary habits without relying on restrictive dieting.
In Singapore, Wegovy is prescribed as part of a doctor-supervised weight loss programme — especially for individuals with a higher BMI or those with weight-related health risks. When used alongside lifestyle changes, Wegovy can support gradual and sustainable fat loss while also improving key markers of metabolic health.
Wegovy offers several clinically proven benefits that make it a valuable option for individuals looking to lose weight under medical supervision in Singapore. Its effectiveness stems from how it targets the body’s natural appetite regulation pathways while supporting long-term adherence through convenient once-weekly dosing.
Wegovy has demonstrated impressive results in clinical trials, with many patients achieving 15% or more in total body weight reduction over time. These results are often superior to those seen with earlier GLP-1 treatments like Saxenda, which requires daily injections. The higher therapeutic dose of semaglutide in Wegovy allows for more consistent appetite suppression and fat loss.
By mimicking the GLP-1 hormone, Wegovy acts directly on appetite-regulating centres in the brain. This leads to reduced hunger, earlier satiety, and better control over food choices — especially helpful for those who struggle with frequent snacking or emotional eating.
Compared to daily treatments like Saxenda or oral medications like Rybelsus, Wegovy’s once-weekly injection schedule makes it easier to maintain over the long term. This convenience plays a big role in improving treatment adherence and outcomes.
Beyond weight reduction, Wegovy may help improve markers such as blood sugar levels, insulin sensitivity, and cholesterol. For individuals with pre-diabetes, fatty liver, or other weight-related conditions, these metabolic improvements can be particularly beneficial.
Wegovy offers an effective, non-invasive alternative to bariatric surgery. Under medical guidance, it becomes part of a structured weight loss plan tailored to each patient’s goals and health status — with ongoing monitoring to ensure safety and progress.
Wegovy may be considered for individuals who are overweight or obese, especially when lifestyle modifications alone have not resulted in meaningful weight loss. It is typically prescribed under medical supervision and is part of a structured weight management programme.
You may be a suitable candidate for Wegovy if you:
Before starting treatment, a medical consultation is required to determine if Wegovy is appropriate. Your doctor will assess your medical history, weight-related health risks, and lifestyle factors to ensure safe and effective use.
Wegovy has been shown to support significant weight loss in both clinical studies and medical practice. It is a once-weekly semaglutide injection that works by helping the body regulate appetite, reduce food intake, and promote a steady reduction in fat mass over time.
In the STEP 1 clinical trial, individuals using Wegovy (2.4 mg weekly semaglutide) lost an average of 14.9% of their starting body weight over 68 weeks. Some participants achieved weight reductions of 20% or more, particularly when treatment was combined with healthier eating habits and increased physical activity.
In Singapore, patients prescribed Wegovy under medical supervision may expect a weight loss range of 5% to 15%, depending on dosage progression, metabolic response, and consistency with lifestyle recommendations.
This gradual and sustained weight loss has been associated with improvements in blood pressure, cholesterol levels, insulin resistance, and overall quality of life.
Wegovy is not intended to cause rapid weight loss, but rather a gradual, medically guided reduction in body weight. The treatment typically follows a dose-escalation protocol to help the body adjust and minimise gastrointestinal side effects.
General treatment timeline:
This structured, step-wise progression allows for better tolerance, long-term adherence, and sustainable weight management.
Individual outcomes on Wegovy vary depending on a number of health and behavioural factors:
While results can differ from person to person, Wegovy is generally well-suited for patients looking for a structured, long-term approach to weight loss supported by clinical data and ongoing supervision.
Starting Wegovy as part of a weight loss programme involves a structured and medically supervised process. The journey is personalised to your health profile and goals, with guidance at every stage to ensure treatment is safe, well-tolerated, and effective.
Your Wegovy journey begins with a detailed consultation. Your doctor will review your BMI, weight history, eating patterns, and any underlying medical conditions such as insulin resistance, fatty liver, or high cholesterol. This helps determine if Wegovy is suitable and ensures there are no contraindications.
If Wegovy is appropriate, your doctor will walk you through what to expect, how the medication works, and how it fits into a broader lifestyle plan.
Wegovy is not started at full strength. The treatment begins at a lower dose and is gradually increased over several weeks to reach the therapeutic maintenance dose of 2.4 mg. This dose-escalation approach helps reduce the risk of gastrointestinal side effects such as nausea, bloating, or reflux.
Your doctor will provide a dosing schedule and adjust it based on how well you tolerate each increase.
Wegovy is administered once a week via a simple subcutaneous injection — typically in the abdomen or thigh. You’ll be shown how to self-inject at home, or the clinic can assist if preferred. The fixed weekly schedule makes it easy to remember and fits into most routines without daily disruption.
Throughout the treatment, follow-up appointments are scheduled to track your progress, monitor side effects, and adjust your care plan if needed. Your doctor may also review blood tests or body composition metrics to ensure that weight loss is both effective and safe.
These check-ins are a key part of the Wegovy journey, helping to keep you on track while offering personalised support.
Wegovy works best when combined with sustainable lifestyle changes. Your doctor may provide practical, non-restrictive strategies to help improve your nutrition, increase movement, manage stress, and develop long-term habits. The goal isn’t just to lose weight — but to support lasting improvements in health and quality of life.
Wegovy is generally well tolerated when prescribed under medical supervision, but like all prescription medications, it may cause side effects. These are typically mild and temporary, especially during the early stages of treatment as the dose is gradually increased.
Most side effects occur during the dose escalation phase and tend to settle once the body adjusts to the medication. Commonly reported symptoms include:
Your doctor may recommend lifestyle tips — such as eating smaller meals, avoiding greasy foods, and staying well-hydrated — to help reduce digestive discomfort during this adjustment period.
While uncommon, more serious side effects have been associated with semaglutide medications like Wegovy. These include:
Wegovy is not recommended for individuals with a personal or family history of medullary thyroid carcinoma (MTC) or those with multiple endocrine neoplasia syndrome type 2 (MEN2).
Before starting Wegovy, your doctor will perform a thorough medical evaluation to assess suitability. This may include reviewing your personal and family medical history, current medications, and relevant lab tests. During treatment, ongoing monitoring ensures any side effects are detected and addressed early.
If you experience persistent, worsening, or unexpected symptoms while on Wegovy, it is important to inform your doctor promptly.
When used as part of a medically supervised programme, Wegovy offers a safe and structured approach to weight loss with an established safety profile supported by clinical trials.
Wegovy is part of a growing class of injectable weight loss treatments used in Singapore for patients struggling with obesity or weight-related health conditions. These treatments are typically prescribed under medical supervision and work by regulating appetite, improving satiety, and supporting metabolic health.
Some of the other injectable options available include:
Each injectable medication has different dosing schedules, active ingredients, and clinical profiles. The right choice depends on your individual health background, weight loss goals, and response to treatment.
At our clinic, all injectable treatments are prescribed only after a comprehensive consultation to ensure medical suitability and safety. Your doctor will help guide you through available options and tailor a treatment plan that fits your needs.
Most patients begin to notice appetite changes within the first few weeks of starting Wegovy. Visible weight loss usually occurs by the second or third month, especially when combined with healthy eating and consistent lifestyle habits. The full effects typically build up over time as the dosage reaches the maintenance level.
There is no fixed diet plan required, but for best results, Wegovy should be used alongside balanced nutrition and regular physical activity. Your doctor may provide personalised lifestyle guidance to help support your weight loss goals in a sustainable way.
The length of treatment varies depending on your starting weight, target goals, and how your body responds. Some individuals use Wegovy for several months, while others may remain on maintenance therapy for longer periods. Your doctor will review your progress regularly and help determine the appropriate treatment duration.
Wegovy may not be suitable for individuals with a history of pancreatitis, certain thyroid conditions, or those who are pregnant or breastfeeding. A medical consultation is necessary to assess your health background and determine if Wegovy is appropriate for you.
Wegovy contains a higher therapeutic dose of semaglutide and is specifically approved for long-term weight management. Saxenda is a daily injection, while Wegovy is taken once weekly. Ozempic also contains semaglutide but is typically prescribed for Type 2 diabetes and sometimes used off-label for weight loss. Mounjaro is a dual-action injectable (GLP-1 + GIP) that is being explored for weight-related use. Your doctor will advise on which treatment is most appropriate based on your profile.
Some individuals may regain weight after stopping treatment, especially if healthy habits are not maintained. To minimise this, the focus during Wegovy treatment includes building sustainable eating and lifestyle patterns that can be continued long term, even after stopping the injection.
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