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Types and Causes of Pigmentation

Pigmentation appears in various forms, each with distinct characteristics and underlying causes. Recognizing the type of pigmentation is crucial for understanding its triggers and planning effective management. Here are the most common types of pigmentation:

Sunspots (Solar Lentigines)

Melasma

Post-Inflammatory Hyperpigmentation (PIH)

Freckles

Age Spots (Liver Spots)

Pigmentation Laser Treatments in Singapore

Laser treatments are among the most effective solutions for addressing various types of pigmentation, including sunspots, melasma, freckles, and post-inflammatory hyperpigmentation (PIH). These treatments target the root cause of pigmentation by breaking down excess melanin in the skin while promoting a clearer, more even complexion. Below are the most commonly used pigmentation lasers in Singapore:

Q-Switched Nd:YAG Laser

The Q-Switched Nd:YAG laser is a widely used laser for pigmentation treatment in Singapore. It emits high-intensity laser pulses that specifically target melanin in the skin.

PICO Laser (Picosecond Laser)

The PICO laser represents a newer generation of pigmentation lasers, delivering ultra-short pulses of laser energy to the skin.

Yellow Laser (Pro Yellow Laser)

The Yellow Laser, such as the Pro Yellow Laser, is another pigmentation treatment option in Singapore, targeting redness and vascular pigmentation. It uses a 577nm wavelength that is effective in targeting both melanin and hemoglobin.

Why Choose Laser Treatments for Pigmentation?

Laser treatments are highly targeted, allowing them to treat specific areas of pigmentation without damaging the surrounding skin. They are versatile and can be customized to suit different skin types and pigmentation concerns.

Key Benefits of Laser Pigmentation Treatments in Singapore

Key Ingredients in Topical Skincare for Pigmentation Treatment in Singapore

The success of topical pigmentation treatments relies heavily on the active ingredients in skincare products. At Edwin Lim Medical Aesthetic Clinic, we use formulations with scientifically proven ingredients to effectively address pigmentation concerns. Here’s a closer look at the key ingredients and their roles in reducing pigmentation:

Tranexamic Acid

Arbutin

4-n-Butylresorcinol

Vitamin C 20%

Niacinamide (Vitamin B3)

Hydroquinone

Tretinoin

Crystal Tomato® Beyond Sun Protection – High-SPF Sunblock for Pigmentation in Singapore

Effective sun protection is a cornerstone of managing and preventing pigmentation. Crystal Tomato® Beyond Sun Protection is a high-performance sunblock designed to address factors that contribute to pigmentation, including UV exposure and environmental stressors. Here's how it supports pigmentation management:

Regular application of Crystal Tomato® Beyond Sun Protection is crucial for those undergoing pigmentation treatments, such as lasers or topical skincare, as it minimizes the risk of new pigmentation and enhances treatment results.

For individuals with pigmentation-prone skin, incorporating a high-SPF sunblock into your skincare routine is a simple yet impactful step toward maintaining a more even skin tone.

Oral Sunblock and Whitening Supplements for Pigmentation Treatment in Singapore

Oral sunblock and whitening supplements offer a convenient and effective way to support pigmentation management. These supplements provide additional protection against UV-induced pigmentation while promoting a brighter and more even skin tone. 

They work by targeting pigmentation at a cellular level, complementing the effects of topical and laser treatments. Below are the key ingredients and their roles in pigmentation treatment:

Colourless Carotenoids

Polypodium Leucotomos

Glutathione

Pine Bark Extract

Vitamin C

Benefits of Oral Sunblock and Whitening Supplements in Singapore

Why Combine Oral Sunblock with Topical Sunscreen?

While oral supplements enhance internal protection, they are most effective when combined with topical sunscreens. Together, they provide comprehensive coverage against UV rays, minimizing pigmentation triggers and supporting the results of other treatments like lasers or topical skincare.

What Are Cortisone and Antibiotic Acne Injections?

Cortisone and antibiotic acne injections are fast-acting treatments used to reduce the size, redness, and pain of inflamed pimples, cystic acne, and nodules. These injections work by targeting deep, stubborn acne that does not respond well to topical treatments or oral medications.

How Do Cortisone and Antibiotic Injections Work?

Who Should Consider Acne Injections?

Benefits of Cortisone and Antibiotic Acne Injections

Cortisone and antibiotic acne injections provide a powerful combination treatment for inflamed, cystic, and nodular acne. By delivering anti-inflammatory and antibacterial effects in a single shot, this treatment works rapidly to reduce swelling, pain, and the risk of scarring.

Rapid Reduction of Swelling and Inflammation

Fast Pain Relief for Deep, Painful Acne

Lowers the Risk of Acne Scarring

Targets Deep, Stubborn Acne Resistant to Other Treatments

Quick, Convenient, and Minimally Invasive

By combining the benefits of cortisone and antibiotics in a single injection, this treatment provides a fast, effective, and targeted solution for severe acne breakouts, helping patients achieve clearer skin with minimal disruption to their daily routine.

What to Expect During a Cortisone and Antibiotic Acne Injection Treatment

Cortisone and antibiotic acne injections are a quick and effective treatment for inflamed pimples, cystic acne, and nodular acne. Understanding what to expect during the procedure can help patients feel more prepared and confident about the treatment process.

Consultation and Assessment

The Injection Procedure

Post-Treatment Care and Recovery

How Soon Can Results Be Seen?

Are Multiple Sessions Required?

Cortisone and antibiotic acne injections offer a fast and effective solution for inflamed acne, providing relief with minimal downtime. The procedure is commonly performed in aesthetic and dermatology clinics in Singapore for those seeking immediate improvement of stubborn acne breakouts.

Side Effects and Risks of Cortisone and Antibiotic Acne Injections

Cortisone and antibiotic acne injections are a reliable treatment option for severe acne, but patients should be aware of potential side effects and risks. These can be categorized into common side effects and rare but possible risks.

Common Side Effects

Rare but Possible Risks

Frequently Asked Questions (FAQ) About Cortisone and Antibiotic Acne Injections in Singapore

Most patients experience a reduction in swelling and inflammation within 24 to 48 hours. The treated pimple continues to heal and flatten over the next few days.

These injections are ideal for individuals with inflamed cystic acne, nodular acne, or large, stubborn pimples. They are not recommended for treating blackheads, whiteheads, or mild acne.

Yes, many patients choose this treatment for quick relief from large pimples before an important event. It is best to have the injection at least 24 hours before the event for optimal results.

Most large pimples require only one injection. Patients with recurring cystic acne may need additional injections as necessary, depending on their condition and response to treatment.

There is no downtime. You can resume your usual activities immediately after the procedure. Mild redness or tenderness at the injection site may occur but typically resolves within a day.

These injections treat current inflamed acne lesions but do not prevent future breakouts. Long-term acne management may include skincare products, oral medications, or treatments such as laser therapy to reduce future breakouts.

The results are effective for treating individual inflamed pimples, but new breakouts may occur. A comprehensive acne treatment plan is essential for long-term skin health and breakout prevention.

Are you searching for an effective solution to under-eye dark circles, fine lines, and early signs of ageing? Polynucleotide (PN) eye injections, also widely recognised as “salmon DNA eye boosters” or “婴儿针眼部疗程” (baby skin booster for eyes), offer a scientifically advanced way to rejuvenate the delicate skin around your eyes.

This popular under-eye rejuvenation treatment in Singapore uses purified polynucleotides—naturally derived from salmon DNA—to stimulate collagen production, repair damaged skin, and improve overall skin elasticity. Sometimes referred to as “PN eye therapy,” “salmon DNA under-eye injections,” or “Korean polynucleotide eye treatment,” this procedure is sought after for its ability to target fine wrinkles, reduce dark circles, and revitalise tired-looking eyes.

Many patients in Singapore choose this injectable eye booster because it is clinically proven to repair thin, crepey under-eye skin and promote a youthful, refreshed appearance without surgery or significant downtime. If you are seeking a solution that goes beyond traditional fillers and creams, polynucleotide under-eye injections could be the answer for brighter, firmer, and more youthful eyes.

What Causes Under-Eye Ageing and Dark Circles?

The under-eye area is often the first part of the face to show visible signs of ageing. This is largely due to the skin in this region being thinner and more delicate than elsewhere on the face. As we age, collagen and elastin production naturally decline, leading to a gradual loss of firmness and elasticity in the skin around the eyes.

Other factors that contribute to under-eye ageing include repeated facial expressions, genetics, sun exposure, and lifestyle factors such as poor sleep or smoking. These factors can cause the formation of fine lines, wrinkles, and puffiness, making the eyes appear tired or older than they are.

Dark circles may also develop as a result of increased pigmentation, thinning skin that reveals underlying blood vessels, or fluid retention. Individuals with a family history of dark circles, as well as those with fair or thin skin, may notice these changes earlier.

Because the under-eye region is both sensitive and prone to early ageing, many patients in Singapore seek targeted treatments—such as polynucleotide (PN) eye injections, salmon DNA eye boosters, and other injectable therapies—to address these common concerns. These treatments focus on improving skin texture, supporting collagen regeneration, and reducing the appearance of dark circles for a more refreshed and youthful look.

How Polynucleotide (PN) 婴儿针 / 丽珠兰 Eye Boosters Work

Polynucleotide (PN) eye injections, often described as “salmon DNA eye boosters” or “婴儿针眼部疗程,” are a non-surgical treatment specifically designed for the delicate under-eye area. This injectable therapy uses highly purified polynucleotides—biomolecules derived from salmon DNA—that are well-tolerated by human skin.

When administered as a series of micro-injections into the under-eye region, polynucleotides act as biological stimulators. They support the skin’s natural healing process by encouraging fibroblast activity, which leads to increased collagen and elastin synthesis. Over time, this may improve skin thickness, elasticity, and hydration—addressing common concerns such as fine lines, wrinkles, and dark circles.

Unlike traditional dermal fillers, which primarily add volume, PN eye boosters focus on tissue repair and skin quality improvement. These salmon DNA-based injections are favoured by patients in Singapore seeking a gradual, natural-looking enhancement to the under-eye area, with minimal risk of overcorrection or lumpiness.

Known in the medical community by terms such as “PN eye rejuvenation,” “salmon DNA eye treatment,” and “Korean polynucleotide therapy,” this procedure is popular for its role in skin restoration and under-eye revitalisation. Results are typically seen after a series of sessions, with ongoing improvements as new collagen forms and the skin becomes more resilient.

Benefits of Polynucleotide (PN) 婴儿针 / 丽珠兰 Eye Injections

Polynucleotide (PN) eye injections—widely recognised as salmon DNA eye boosters, PN eye therapy, or Korean polynucleotide under-eye treatments—are a popular non-surgical solution in Singapore for those seeking under-eye rejuvenation. Below are the key benefits of this treatment:

Reduction of Dark Circles

PN eye injections improve microcirculation and support the repair of delicate under-eye skin. This process can help lighten dark circles, particularly those caused by thinning skin and increased pigmentation.

Improvement of Fine Lines and Wrinkles

The bioactive polynucleotides in salmon DNA-based injections stimulate collagen and elastin synthesis. This results in smoother, firmer skin and a visible reduction in fine lines, crepey texture, and early wrinkles around the eyes.

Enhanced Skin Hydration and Elasticity

PN eye boosters are known for their hydrophilic properties, which help attract and retain moisture within the skin. Improved hydration supports skin suppleness and resilience in the under-eye area.

Restoration of Skin Quality

Polynucleotide eye therapy encourages cellular repair and regeneration. Over time, this can improve overall skin tone, texture, and thickness, restoring the quality of the periorbital skin.

Natural-Looking Results

Unlike traditional fillers, PN eye injections do not add volume but instead focus on supporting the skin’s natural structure. This leads to subtle, refreshed results without an overfilled or artificial look.

Minimally Invasive With Low Downtime

As a non-surgical treatment, polynucleotide eye therapy involves a series of micro-injections that typically require minimal recovery time. Most patients experience only mild swelling or small bumps, which subside within a few days, allowing for a quick return to normal activities.

Suitable for Various Skin Types

PN eye injections are suitable for a broad range of skin types and tones. This versatility makes them a reliable choice for individuals in Singapore looking for safe and effective under-eye rejuvenation.

Who Is Suitable for Polynucleotide (PN) 婴儿针 / 丽珠兰 Eye Injections?

Polynucleotide (PN) eye injections—also known as salmon DNA eye boosters, PN eye therapy, or Korean polynucleotide under-eye treatments—are appropriate for a broad spectrum of individuals looking to address specific under-eye concerns.

Suitable Candidates for PN Eye Injections

You may be an ideal candidate for PN eye injections if you:

Who Should Avoid PN Eye Injections?

While PN eye injections are suitable for most adults, some individuals should postpone or avoid this treatment:

Age and Skin Type Considerations

PN eye therapy is suitable for both men and women and is effective across a variety of skin types and ages. Whether you are experiencing early signs of ageing or seeking to prevent further under-eye deterioration, polynucleotide injections can be tailored to your needs.

Medical Assessment Is Essential

A thorough assessment by a qualified medical professional is recommended before undergoing PN eye injections. This ensures the treatment plan is safe, appropriate, and customised to address your specific under-eye concerns.

PN Eye Injection Treatment Process in Singapore

Polynucleotide (PN) eye injections—sometimes called salmon DNA eye boosters, PN eye therapy, or Korean polynucleotide under-eye treatment—are designed to deliver safe, targeted rejuvenation for the delicate skin around the eyes. Here’s what you can expect during a typical session in Singapore:

Consultation and Personalised Assessment

Your journey begins with a detailed consultation. Dr Edwin will assess your under-eye area, discuss your goals, and determine if PN eye injections are appropriate for your specific needs. This step ensures a tailored approach based on your skin concerns and medical history.

Skin Preparation

The under-eye region will be gently cleansed to create a sterile surface. A topical numbing cream is usually applied to enhance comfort during the procedure. This preparation phase generally takes 20–30 minutes.

Precise Microinjections of Polynucleotides

Highly purified polynucleotides (PN)—derived from salmon DNA and widely used in advanced Korean eye rejuvenation—are carefully administered as a series of microinjections directly into the skin around the eyes.

These injections are placed at strategic points to address issues such as fine lines, dark circles, and thinning skin. The actual injection process typically takes about 15–20 minutes.

Post-Treatment Care

After the procedure, an intensive recovery cream is gently massaged into the treated area to promote healing and comfort. It is normal to experience small bumps and mild swelling immediately after the session; these usually resolve within 3–5 days. Because the under-eye skin is delicate, some bruising may occur and can take up to a week to subside.

You will receive detailed aftercare instructions to support optimal healing and reduce the risk of side effects. Following these guidelines helps ensure the best results from your PN eye therapy.

Minimal Downtime and Recovery

One of the main advantages of PN eye injections is the minimal downtime required. Most individuals can return to daily activities soon after treatment, making this an efficient and practical option for busy patients in Singapore.

Side Effects and Risks of Polynucleotide (PN) 婴儿针 / 丽珠兰 Eye Injections

Polynucleotide (PN) eye injections—also known as salmon DNA eye boosters, PN eye therapy, or Korean polynucleotide under-eye treatment—are considered a minimally invasive procedure for under-eye rejuvenation. However, as with any medical treatment, there are potential side effects and risks to consider. Understanding these effects allows patients to make informed decisions and set realistic expectations.

Common Side Effects

Rare Side Effects

Safety Profile

PN eye injections have an established safety profile when performed by experienced medical professionals using proper techniques. Most side effects are mild, temporary, and self-limiting. Serious complications are uncommon but can be further minimised by careful patient selection and adherence to aftercare guidelines.

What to Do if You Experience Side Effects

If you experience prolonged redness, swelling, pain, or other symptoms after your PN eye treatment, contact your practitioner for further assessment and guidance. Prompt management of any unexpected side effects can help ensure a smooth recovery and optimal treatment outcomes.

Results and What to Expect After Polynucleotide (PN) 婴儿针 / 丽珠兰 Eye Injections

Polynucleotide (PN) eye injections—also described as salmon DNA eye boosters, PN eye therapy, or Korean polynucleotide under-eye treatment—are designed to deliver gradual and natural-looking improvement to the under-eye area.

When Will Results Be Visible?

Most patients begin to notice initial improvements in skin hydration, texture, and fine lines within 1 to 2 weeks after their first session. As collagen production and cellular repair continue, further enhancements in skin quality and the reduction of dark circles typically become visible over the following weeks.

How Many Sessions Are Needed?

A typical treatment protocol in Singapore involves a series of 3 sessions spaced about 4 weeks apart. The number of sessions required may vary depending on the severity of under-eye concerns and individual response to treatment. Maintenance sessions every 6 to 12 months may be recommended to sustain results.

Expected Improvements

Duration of Results

The benefits of polynucleotide under-eye injections are long-lasting, with many individuals enjoying visible improvements for up to 9 to 12 months after completing the initial treatment course. Maintenance sessions help prolong and enhance these results over time.

Realistic Expectations

While most patients achieve significant improvement, results may vary depending on individual skin condition, age, lifestyle factors, and adherence to recommended aftercare. A personalised treatment plan and realistic expectations are essential for optimal satisfaction.

Combination Treatments for Under-Eye Rejuvenation

While polynucleotide (PN) eye injections—commonly known as salmon DNA eye boosters or PN eye therapy—provide significant benefits for skin quality and dark circles, optimal under-eye rejuvenation can often be achieved through a combination of complementary treatments. In Singapore, many clinics offer integrated protocols for more comprehensive and long-lasting results.

PN Eye Injections with Botulinum Toxin for Fine Lines and Wrinkles

Botulinum toxin eye wrinkle injections are frequently used alongside PN eye therapy to target dynamic wrinkles, such as crow’s feet, around the eyes. Botulinum toxin works by temporarily relaxing the underlying muscles responsible for wrinkle formation.

When combined with polynucleotide injections, this approach addresses both skin texture and muscle activity, leading to smoother and more youthful-looking eyes. The dual strategy is effective in softening existing lines while supporting ongoing collagen regeneration and skin repair.

PN Eye Therapy and HIFU for Eye Bags and Lifting

High-Intensity Focused Ultrasound (HIFU) is a non-invasive energy-based treatment that delivers focused ultrasound waves to tighten and lift the skin around the eyes. When used in combination with PN eye injections, HIFU helps reduce the appearance of mild to moderate eye bags and sagging by improving skin firmness and contour.

The skin-repairing effects of polynucleotide therapy complement the lifting action of HIFU, making this pairing suitable for individuals seeking comprehensive under-eye rejuvenation without surgery.

Under-Eye (Tear Trough) Fillers for Sunken Undereyes and PN Eye Treatments

In cases where under-eye hollowness or deep tear troughs contribute to a tired or sunken appearance, hyaluronic acid (HA) fillers may be recommended in combination with polynucleotide (PN) eye injections. Tear trough fillers are designed to restore lost volume beneath the eyes, smooth out depressions, and create a more even transition between the lower eyelid and the cheek.

When used together, PN eye therapy supports skin quality, hydration, and collagen production, while tear trough fillers provide immediate volumisation and structural support. This synergistic approach addresses both the skin’s surface and underlying contour, offering comprehensive under-eye rejuvenation.

Treatment with HA fillers should be performed by an experienced practitioner to minimise the risk of complications and ensure natural-looking results. Combining tear trough fillers with PN eye boosters is particularly beneficial for patients seeking to correct both volume loss and poor skin texture in the under-eye area.

Personalised Combination Approaches

A customised treatment plan—combining PN eye boosters with botulinum toxin, HIFU, or other therapies such as hyaluronic acid fillers—can be tailored to your unique under-eye concerns. During your consultation, a medical professional will assess your skin quality, degree of laxity, and the presence of dynamic wrinkles or puffiness to recommend the most effective combination strategy.

Combining these evidence-based modalities allows for a multi-layered approach to under-eye rejuvenation, addressing texture, tone, firmness, and expression lines for a balanced and natural outcome.

Frequently Asked Questions About Polynucleotide (Eye) 婴儿针 / 丽珠兰 Anti-Aging Treatment

Yes, Rejuran I (Eye) is specifically designed for the thin and sensitive skin around the eyes. Its biocompatible polynucleotide formulation ensures safety and minimizes the risk of adverse reactions when administered by a qualified doctor.

A standard treatment protocol usually involves 3 to 4 sessions spaced 3 to 4 weeks apart. This approach allows polynucleotides to stimulate gradual collagen production. Maintenance sessions every 6 to 12 months help sustain results, similar to established Rejuran I (Eye) protocols in Singapore.

The procedure involves a series of microinjections under the eyes. To minimise discomfort, a topical numbing cream is applied before treatment. Most patients describe only mild discomfort or a brief pinching sensation. Recovery is quick, with Rejuran I (Eye)–based PN solutions integrating smoothly into the skin.

When administered by a qualified medical professional, PN eye injections—such as those using Rejuran I (Eye)—have a strong safety profile. Mild redness, swelling, and temporary bumps are the most common side effects. Bruising may also occur but usually resolves within a week. Rarely, allergic reactions or infections can occur. Comprehensive assessment and aftercare minimise these risks.

Yes. It is common to combine Botox (for crow’s feet) and HIFU (for eye bag reduction and skin tightening) with PN eye injections for comprehensive under-eye rejuvenation. Many clinics in Singapore use this approach, often including Rejuran I (Eye) as part of their combination protocols.

Downtime is minimal. Mild swelling and small bumps generally subside within 3 to 5 days, and any bruising usually resolves in about 7 days. Patients can usually resume daily activities soon after treatment. Proper post-treatment care supports rapid recovery after Rejuran I (Eye) therapy.

Individuals who are pregnant, breastfeeding, have active skin infections, known allergies to injectable ingredients, or a history of abnormal wound healing should avoid this treatment. A thorough consultation ensures that Rejuran I (Eye)–based PN therapy is appropriate and safe for each patient.

Yes, PN eye injections can be safely combined with hyaluronic acid tear trough fillers to address both volume loss and skin quality under the eyes. This dual approach is often used in clinics, with polynucleotide injections such as Rejuran I (Eye) supporting collagen regeneration while fillers restore volume and structure.

Each session typically takes about 30 to 45 minutes, including preparation time, numbing, and the actual microinjections. The procedure with Rejuran I (Eye) is performed in-clinic and does not require general anaesthesia.

After PN eye injections, patients should avoid rubbing the treated area, intense exercise, excessive heat, and facial massages for 24 to 48 hours. Following specific aftercare instructions is important to support optimal results and minimise swelling or bruising after Rejuran I (Eye) treatment.

It is generally recommended to wait at least 24 hours before applying makeup to the treated area. This helps prevent irritation or infection while the microinjection sites from Rejuran I (Eye) heal.

Results from PN eye injections are not permanent. Most patients experience benefits that last 6 to 12 months, after which maintenance sessions with Rejuran I (Eye) may be recommended to sustain improvements.

PN eye injections, including Rejuran I (Eye), do not add bulk or create puffiness. Unlike fillers, polynucleotide therapy works by stimulating the skin’s own collagen production and cellular repair for natural-looking results without volume overload.

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