Are you searching for an effective solution to under-eye dark circles, fine lines, and early signs of ageing? Polynucleotide (PN) eye injections, also widely recognised as “salmon DNA eye boosters” or “婴儿针眼部疗程” (baby skin booster for eyes), offer a scientifically advanced way to rejuvenate the delicate skin around your eyes.
This popular under-eye rejuvenation treatment in Singapore uses purified polynucleotides—naturally derived from salmon DNA—to stimulate collagen production, repair damaged skin, and improve overall skin elasticity. Sometimes referred to as “PN eye therapy,” “salmon DNA under-eye injections,” or “Korean polynucleotide eye treatment,” this procedure is sought after for its ability to target fine wrinkles, reduce dark circles, and revitalise tired-looking eyes.
Many patients in Singapore choose this injectable eye booster because it is clinically proven to repair thin, crepey under-eye skin and promote a youthful, refreshed appearance without surgery or significant downtime. If you are seeking a solution that goes beyond traditional fillers and creams, polynucleotide under-eye injections could be the answer for brighter, firmer, and more youthful eyes.
The under-eye area is often the first part of the face to show visible signs of ageing. This is largely due to the skin in this region being thinner and more delicate than elsewhere on the face. As we age, collagen and elastin production naturally decline, leading to a gradual loss of firmness and elasticity in the skin around the eyes.
Other factors that contribute to under-eye ageing include repeated facial expressions, genetics, sun exposure, and lifestyle factors such as poor sleep or smoking. These factors can cause the formation of fine lines, wrinkles, and puffiness, making the eyes appear tired or older than they are.
Dark circles may also develop as a result of increased pigmentation, thinning skin that reveals underlying blood vessels, or fluid retention. Individuals with a family history of dark circles, as well as those with fair or thin skin, may notice these changes earlier.
Because the under-eye region is both sensitive and prone to early ageing, many patients in Singapore seek targeted treatments—such as polynucleotide (PN) eye injections, salmon DNA eye boosters, and other injectable therapies—to address these common concerns. These treatments focus on improving skin texture, supporting collagen regeneration, and reducing the appearance of dark circles for a more refreshed and youthful look.
Polynucleotide (PN) eye injections, often described as “salmon DNA eye boosters” or “婴儿针眼部疗程,” are a non-surgical treatment specifically designed for the delicate under-eye area. This injectable therapy uses highly purified polynucleotides—biomolecules derived from salmon DNA—that are well-tolerated by human skin.
When administered as a series of micro-injections into the under-eye region, polynucleotides act as biological stimulators. They support the skin’s natural healing process by encouraging fibroblast activity, which leads to increased collagen and elastin synthesis. Over time, this may improve skin thickness, elasticity, and hydration—addressing common concerns such as fine lines, wrinkles, and dark circles.
Unlike traditional dermal fillers, which primarily add volume, PN eye boosters focus on tissue repair and skin quality improvement. These salmon DNA-based injections are favoured by patients in Singapore seeking a gradual, natural-looking enhancement to the under-eye area, with minimal risk of overcorrection or lumpiness.
Known in the medical community by terms such as “PN eye rejuvenation,” “salmon DNA eye treatment,” and “Korean polynucleotide therapy,” this procedure is popular for its role in skin restoration and under-eye revitalisation. Results are typically seen after a series of sessions, with ongoing improvements as new collagen forms and the skin becomes more resilient.
Polynucleotide (PN) eye injections—widely recognised as salmon DNA eye boosters, PN eye therapy, or Korean polynucleotide under-eye treatments—are a popular non-surgical solution in Singapore for those seeking under-eye rejuvenation. Below are the key benefits of this treatment:
PN eye injections improve microcirculation and support the repair of delicate under-eye skin. This process can help lighten dark circles, particularly those caused by thinning skin and increased pigmentation.
The bioactive polynucleotides in salmon DNA-based injections stimulate collagen and elastin synthesis. This results in smoother, firmer skin and a visible reduction in fine lines, crepey texture, and early wrinkles around the eyes.
PN eye boosters are known for their hydrophilic properties, which help attract and retain moisture within the skin. Improved hydration supports skin suppleness and resilience in the under-eye area.
Polynucleotide eye therapy encourages cellular repair and regeneration. Over time, this can improve overall skin tone, texture, and thickness, restoring the quality of the periorbital skin.
Unlike traditional fillers, PN eye injections do not add volume but instead focus on supporting the skin’s natural structure. This leads to subtle, refreshed results without an overfilled or artificial look.
As a non-surgical treatment, polynucleotide eye therapy involves a series of micro-injections that typically require minimal recovery time. Most patients experience only mild swelling or small bumps, which subside within a few days, allowing for a quick return to normal activities.
PN eye injections are suitable for a broad range of skin types and tones. This versatility makes them a reliable choice for individuals in Singapore looking for safe and effective under-eye rejuvenation.
Polynucleotide (PN) eye injections—also known as salmon DNA eye boosters, PN eye therapy, or Korean polynucleotide under-eye treatments—are appropriate for a broad spectrum of individuals looking to address specific under-eye concerns.
You may be an ideal candidate for PN eye injections if you:
While PN eye injections are suitable for most adults, some individuals should postpone or avoid this treatment:
PN eye therapy is suitable for both men and women and is effective across a variety of skin types and ages. Whether you are experiencing early signs of ageing or seeking to prevent further under-eye deterioration, polynucleotide injections can be tailored to your needs.
A thorough assessment by a qualified medical professional is recommended before undergoing PN eye injections. This ensures the treatment plan is safe, appropriate, and customised to address your specific under-eye concerns.
Polynucleotide (PN) eye injections—sometimes called salmon DNA eye boosters, PN eye therapy, or Korean polynucleotide under-eye treatment—are designed to deliver safe, targeted rejuvenation for the delicate skin around the eyes. Here’s what you can expect during a typical session in Singapore:
Your journey begins with a detailed consultation. Dr Edwin will assess your under-eye area, discuss your goals, and determine if PN eye injections are appropriate for your specific needs. This step ensures a tailored approach based on your skin concerns and medical history.
The under-eye region will be gently cleansed to create a sterile surface. A topical numbing cream is usually applied to enhance comfort during the procedure. This preparation phase generally takes 20–30 minutes.
Highly purified polynucleotides (PN)—derived from salmon DNA and widely used in advanced Korean eye rejuvenation—are carefully administered as a series of microinjections directly into the skin around the eyes.
These injections are placed at strategic points to address issues such as fine lines, dark circles, and thinning skin. The actual injection process typically takes about 15–20 minutes.
After the procedure, an intensive recovery cream is gently massaged into the treated area to promote healing and comfort. It is normal to experience small bumps and mild swelling immediately after the session; these usually resolve within 3–5 days. Because the under-eye skin is delicate, some bruising may occur and can take up to a week to subside.
You will receive detailed aftercare instructions to support optimal healing and reduce the risk of side effects. Following these guidelines helps ensure the best results from your PN eye therapy.
One of the main advantages of PN eye injections is the minimal downtime required. Most individuals can return to daily activities soon after treatment, making this an efficient and practical option for busy patients in Singapore.
Polynucleotide (PN) eye injections—also known as salmon DNA eye boosters, PN eye therapy, or Korean polynucleotide under-eye treatment—are considered a minimally invasive procedure for under-eye rejuvenation. However, as with any medical treatment, there are potential side effects and risks to consider. Understanding these effects allows patients to make informed decisions and set realistic expectations.
PN eye injections have an established safety profile when performed by experienced medical professionals using proper techniques. Most side effects are mild, temporary, and self-limiting. Serious complications are uncommon but can be further minimised by careful patient selection and adherence to aftercare guidelines.
If you experience prolonged redness, swelling, pain, or other symptoms after your PN eye treatment, contact your practitioner for further assessment and guidance. Prompt management of any unexpected side effects can help ensure a smooth recovery and optimal treatment outcomes.
Polynucleotide (PN) eye injections—also described as salmon DNA eye boosters, PN eye therapy, or Korean polynucleotide under-eye treatment—are designed to deliver gradual and natural-looking improvement to the under-eye area.
Most patients begin to notice initial improvements in skin hydration, texture, and fine lines within 1 to 2 weeks after their first session. As collagen production and cellular repair continue, further enhancements in skin quality and the reduction of dark circles typically become visible over the following weeks.
A typical treatment protocol in Singapore involves a series of 3 sessions spaced about 4 weeks apart. The number of sessions required may vary depending on the severity of under-eye concerns and individual response to treatment. Maintenance sessions every 6 to 12 months may be recommended to sustain results.
The benefits of polynucleotide under-eye injections are long-lasting, with many individuals enjoying visible improvements for up to 9 to 12 months after completing the initial treatment course. Maintenance sessions help prolong and enhance these results over time.
While most patients achieve significant improvement, results may vary depending on individual skin condition, age, lifestyle factors, and adherence to recommended aftercare. A personalised treatment plan and realistic expectations are essential for optimal satisfaction.
While polynucleotide (PN) eye injections—commonly known as salmon DNA eye boosters or PN eye therapy—provide significant benefits for skin quality and dark circles, optimal under-eye rejuvenation can often be achieved through a combination of complementary treatments. In Singapore, many clinics offer integrated protocols for more comprehensive and long-lasting results.
Botulinum toxin eye wrinkle injections are frequently used alongside PN eye therapy to target dynamic wrinkles, such as crow’s feet, around the eyes. Botulinum toxin works by temporarily relaxing the underlying muscles responsible for wrinkle formation.
When combined with polynucleotide injections, this approach addresses both skin texture and muscle activity, leading to smoother and more youthful-looking eyes. The dual strategy is effective in softening existing lines while supporting ongoing collagen regeneration and skin repair.
High-Intensity Focused Ultrasound (HIFU) is a non-invasive energy-based treatment that delivers focused ultrasound waves to tighten and lift the skin around the eyes. When used in combination with PN eye injections, HIFU helps reduce the appearance of mild to moderate eye bags and sagging by improving skin firmness and contour.
The skin-repairing effects of polynucleotide therapy complement the lifting action of HIFU, making this pairing suitable for individuals seeking comprehensive under-eye rejuvenation without surgery.
In cases where under-eye hollowness or deep tear troughs contribute to a tired or sunken appearance, hyaluronic acid (HA) fillers may be recommended in combination with polynucleotide (PN) eye injections. Tear trough fillers are designed to restore lost volume beneath the eyes, smooth out depressions, and create a more even transition between the lower eyelid and the cheek.
When used together, PN eye therapy supports skin quality, hydration, and collagen production, while tear trough fillers provide immediate volumisation and structural support. This synergistic approach addresses both the skin’s surface and underlying contour, offering comprehensive under-eye rejuvenation.
Treatment with HA fillers should be performed by an experienced practitioner to minimise the risk of complications and ensure natural-looking results. Combining tear trough fillers with PN eye boosters is particularly beneficial for patients seeking to correct both volume loss and poor skin texture in the under-eye area.
A customised treatment plan—combining PN eye boosters with botulinum toxin, HIFU, or other therapies such as hyaluronic acid fillers—can be tailored to your unique under-eye concerns. During your consultation, a medical professional will assess your skin quality, degree of laxity, and the presence of dynamic wrinkles or puffiness to recommend the most effective combination strategy.
Combining these evidence-based modalities allows for a multi-layered approach to under-eye rejuvenation, addressing texture, tone, firmness, and expression lines for a balanced and natural outcome.
What Results Can I Expect From Polynucleotide (PN) Eye Injections?
Yes, Rejuran I (Eye) is specifically designed for the thin and sensitive skin around the eyes. Its biocompatible polynucleotide formulation ensures safety and minimizes the risk of adverse reactions when administered by a qualified doctor.
How Many Sessions Of PN Eye Injections Are Needed?
A standard treatment protocol usually involves 3 to 4 sessions spaced 3 to 4 weeks apart. This approach allows polynucleotides to stimulate gradual collagen production. Maintenance sessions every 6 to 12 months help sustain results, similar to established Rejuran I (Eye) protocols in Singapore.
Are PN Eye Injections Painful?
The procedure involves a series of microinjections under the eyes. To minimise discomfort, a topical numbing cream is applied before treatment. Most patients describe only mild discomfort or a brief pinching sensation. Recovery is quick, with Rejuran I (Eye)–based PN solutions integrating smoothly into the skin.
Are PN Eye Injections Safe?
When administered by a qualified medical professional, PN eye injections—such as those using Rejuran I (Eye)—have a strong safety profile. Mild redness, swelling, and temporary bumps are the most common side effects. Bruising may also occur but usually resolves within a week. Rarely, allergic reactions or infections can occur. Comprehensive assessment and aftercare minimise these risks.
Can PN Eye Injections Be Combined With Botulinum Toxin Or HIFU?
Yes. It is common to combine Botox (for crow’s feet) and HIFU (for eye bag reduction and skin tightening) with PN eye injections for comprehensive under-eye rejuvenation. Many clinics in Singapore use this approach, often including Rejuran I (Eye) as part of their combination protocols.
Is There Any Downtime After PN Eye Injections?
Downtime is minimal. Mild swelling and small bumps generally subside within 3 to 5 days, and any bruising usually resolves in about 7 days. Patients can usually resume daily activities soon after treatment. Proper post-treatment care supports rapid recovery after Rejuran I (Eye) therapy.
Who Should Avoid PN Eye Injections?
Individuals who are pregnant, breastfeeding, have active skin infections, known allergies to injectable ingredients, or a history of abnormal wound healing should avoid this treatment. A thorough consultation ensures that Rejuran I (Eye)–based PN therapy is appropriate and safe for each patient.
Can PN Eye Injections Be Combined With Tear Trough Fillers?
Yes, PN eye injections can be safely combined with hyaluronic acid tear trough fillers to address both volume loss and skin quality under the eyes. This dual approach is often used in clinics, with polynucleotide injections such as Rejuran I (Eye) supporting collagen regeneration while fillers restore volume and structure.
How Long Does A PN Eye Injection Session Take?
Each session typically takes about 30 to 45 minutes, including preparation time, numbing, and the actual microinjections. The procedure with Rejuran I (Eye) is performed in-clinic and does not require general anaesthesia.
What Should I Avoid After PN Eye Injections?
After PN eye injections, patients should avoid rubbing the treated area, intense exercise, excessive heat, and facial massages for 24 to 48 hours. Following specific aftercare instructions is important to support optimal results and minimise swelling or bruising after Rejuran I (Eye) treatment.
How Soon Can I Wear Makeup After PN Eye Injections?
It is generally recommended to wait at least 24 hours before applying makeup to the treated area. This helps prevent irritation or infection while the microinjection sites from Rejuran I (Eye) heal.
Are Results From PN Eye Injections Permanent?
Results from PN eye injections are not permanent. Most patients experience benefits that last 6 to 12 months, after which maintenance sessions with Rejuran I (Eye) may be recommended to sustain improvements.
Will PN Eye Injections Cause Puffiness Or Overfilling?
PN eye injections, including Rejuran I (Eye), do not add bulk or create puffiness. Unlike fillers, polynucleotide therapy works by stimulating the skin’s own collagen production and cellular repair for natural-looking results without volume overload.
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